0000019944 00000 n << /N 278 0 R /P 39 0 R /R [ 54 56 293 257 ] /T 265 0 R /V 276 0 R >> Wyatt KM, Dimmock PW, Walker TJ, O’Brien P: Determination of total menstrual blood loss. Google Scholar. https://doi.org/10.1186/2008-2231-22-45, DOI: https://doi.org/10.1186/2008-2231-22-45, Over 10 million scientific documents at your fingertips, Not logged in Qaraaty, M., Kamali, S.H., Dabaghian, F.H. endobj FHD analyzed and interpreted the data. Hum Exp Toxicol. Effect of myrtle fruit syrup on abnormal uterine bleeding: a randomized double-blind, placebo-controlled pilot study. PubMed  0000007018 00000 n 288 0 obj 2012, 15 (3): 75-84. Google Scholar. Traditional Medicine Clinical Trial Research Center, Shahed University, Tehran, Iran, Department of Traditional Medicine, Faculty of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran, Research Institute for Islamic and Complementary Medicine, Iran University of Medical Sciences, Tehran, Iran, Department of Gynecology and Obstetrics, Faculty of Medical Sciences, Shahed University, Tehran, Iran, Department of Traditional Medicine, School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran, Department of Traditional Pharmacy, Faculty of Traditional Medicine, Tehran University of Medical Sciences, Tehran, Iran, Department of Pharmacognosy, School of Pharmacy Shahid Beheshti University of Medical Sciences, Tehran, Iran, Department of Drug and Food control, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran, Department of Gynecology and Obstetrics, Tehran University of Medical Sciences, Tehran, Iran, Medicinal Plant Research Centre, Shahed University, Tehran, Iran, You can also search for this author in Seyed Hamid Kamali or Nafiseh Zafarghandi. << /N 284 0 R /P 70 0 R /R [ 302 56 541 310 ] /T 265 0 R /V 282 0 R >> 287 0 obj stream 304 0 obj 300 0 obj Google Scholar. 278 0 obj The quality of life improved among the subjects in the syrup-treated group. DARU J Pharm Sci. 0000033462 00000 n %PDF-1.3 AUB involves two-thirds of all hysterectomies leading to several complications [14, 15]. DARU Journal of Pharmaceutical Sciences << /N 273 0 R /P 290 0 R /R [ 54 154 293 259 ] /T 265 0 R /V 271 0 R >> Fruit syrups are ridiculously easy to make, and serve endless purposes. 305 0 obj << /Border [ 0 0 0 ] /Dest /Rect [ 419.9809875488 241.2850036621 424.799987793 251.0930023193 ] /Subtype /Link /Type /Annot >> Firstly, ITM has two groups of principal variables: one is part of human nature, mezaj (temperament), racial/ethnic, sex, age, season, zone, profession [40], and the second factor is the composition of the herbal preparations which may vary based on the geographical habitat of the plant, the climate, and the time of reaping [41]. Ibn-e-sina AH: Al-Qanun fit-tib [The Canon of Medicine]. 293 0 obj 1, Mozaffarian V: Trees and Shrubs of Iran. << /Border [ 0 0 0 ] /Dest /Rect [ 116.2200012207 181.3040008545 121.0390014648 191.1119995117 ] /Subtype /Link /Type /Annot >> In two studies, Ginger capsules and myrtle fruit syrup significantly reduced the menstrual duration and blood loss compared with placebo based on the pictorial blood loss assessment chart score (p < 0.001, p = 0.01). << /N 279 0 R /P 39 0 R /R [ 302 56 541 257 ] /T 265 0 R /V 277 0 R >> Based on the current novel results, a therapeutic role of myrtle syrup is suggested for women with AUB-MM, which is accessible and cost-effective therapy. Endometrial synthesis of PGs and signaling in women with profuse menstruation is greater than women with normal menstrual bleeding [4]. The information was recorded at the beginning of the treatment and at the end of each menstrual cycle. Jensen JT, Parke S, Mellinger U, Machlitt A, Fraser IS: Effective treatment of heavy menstrual bleeding with estradiol valerate and dienogest: a randomized controlled trial. endobj Cite this article. 272 0 obj 2010, 6 (21): 9-, PubMed Central  endobj You will smell delicious when using this soap! Canonico M, Oger E, Plu-Bureau G, Conard J, Meyer G, Lévesque H, Trillot N, Barrellier MT, Wahl D, Emmerich J, the ESTHER study: Hormone therapy and venous thromboembolism among postmenopausal women impact of the route of estrogen administration and progestogens. The results of this study showed that myrtle syrup had notable advantages over placebo in women with AUB-MM. Also, the quality of life was significantly improved in the intervention group with minor side effects. Abnormal uterine bleeding (AUB) is one of the main reasons of visiting gynecologists [1]. 0000047991 00000 n you are unable to locate the licence and re-use information, << /A 315 0 R /Border [ 0 0 0 ] /Rect [ 264.1319885254 67.2379989624 379.842010498 74.2679977417 ] /Subtype /Link /Type /Annot >> Myrtle berries extract has ulcer-protective properties [26] and anti-inflammatory effects [27]. Anti-inflammatory activities of anthocyanins have been proven in some studies [36]. In the present study, the subjects received syrup only for three cycles; therefore we cannot comment on any long-term efficacy of myrtle syrup. 0000006502 00000 n 285 0 obj endobj You can store it in the fridge and use it all week. Myrtle (Myrtus communis L.) has been used in the Iranian Traditional Medicine as a treatment for abnormal uterine bleeding-menometrorrhagia. << /N 276 0 R /P 1 0 R /R [ 54 56 293 208 ] /T 265 0 R /V 274 0 R >> xref 2005, 89 (2): 156-157. Yoghurt and fresh strawberries, to serve. Hum Reprod Update. 0000015923 00000 n H��W=��0��W�F����- P"��C (���ϛ����.���ꤜ_��̼y3��HAi�NiW\R�����|G�������S�2�#��ũd�N֫����MHJR�O��"m��]a��g3��f��BJ�j+�7���ɌR�gV�¨xF>����G��gŽ�/� (����0��������DF��� �9�C���D�d�n���N�T�UL̖�9Љ�6�͉,���-: ���3E��u�>�_l��J8�4��$�K�f���g�7�z�g��C��}��}��~!�Z�����u�]@��G��u�} �qB�y�Gr��Ś@�ˠƁ������G����Ϩ 6C3 m�`Oh2�Ep|P>��d�H;�2�`3�;"�pf�Ύd�ƃ�2���1�0�``̐;�����E:`���l9�j�=XD���� �3��K�6�M��sRI��aw!F���+S��Ɂ����5�@[�. Google Scholar, Critchley HO, Maybin JA: Molecular and cellular causes of abnormal uterine bleeding of endometrial origin. 276 0 obj endobj << /N 270 0 R /P 290 0 R /R [ 54 546 293 563 ] /T 265 0 R /V 268 0 R >> 0000022061 00000 n 0000034980 00000 n Therefore, the presence of the effective anti-inflammatory components in the myrtle extract can render the myrtle syrup a potential source to reduce prostaglandin secretion and to cure AUB subsequently. 0000032178 00000 n Livingstone M, Fraser IS: Mechanisms of abnormal uterine bleeding. Some studies have demonstrated that flavonoids can inhibit inflammatory mediators [37]. All authors read and approved the final manuscript. CAS  Myrtle ( Myrtus communis L.) has been used in the Iranian Traditional Medicine as a treatment for abnormal uterine bleeding-menometrorrhagia. Background: Myrtle (Myrtus communis L.) has been used in the Iranian Traditional Medicine as a treatment for abnormal uterine bleeding-menometrorrhagia. The main aim of this study is to evaluate the effect of myrtle fruit syrup on abnormal uterine bleeding-menometrorrhagia. It can also be used as a cordial base, and makes a refreshing cooling long drink when mixed with soda water. Traditional decoction was prepared as described in “Qarabadin” (Ghayeni, Qarabadin-e-Salehi, 1765 AD; Aghili, Qarabadin-e-Kabir, 1781 AD) [29, 30] texts belonging to ITM pharmaceutical discipline. endobj 0000002683 00000 n During luteal phase in menstrual cycle, some inflammatory processes lead to tissue edema in endometrium and continue with excessive menstrual bleeding (EMB).